Things go better with Coke! Or do they?

This turned up in the mainstream meeja last week: 

“COCA-Cola and Pepsi say they have lowered levels of a chemical in caramel colouring which has been found to cause cancer in lab tests.

The move allows the companies to avoid having to label products with a cancer warning due to a California law setting safe levels of 4-methylimidazole.

Both drinkmakers said their popular and highly secretive recipes will not be altered but that caramel suppliers have been asked to reduce 4-MEI levels in California, a change that will eventually spread across the United States and - at least in Coke's case - around the world.

"We are NOT changing our recipe; or our formula," Coca-Cola Company spokesman Ben Sheidler said in an email.

"What we did do is direct our caramel suppliers to make a manufacturing process modification in order to reduce the level of 4-MEI in our caramel so as to meet the requirement set by the state of California's Proposition 65."

For its part, PepsiCo said its beverages "are and always will be safe for consumption."

"Consumers will notice no difference in our products and have no reason at all for any health concerns. There is no scientific evidence that 4-MEI in foods and beverages is a threat to human health," it added.” {new.com.au 10^th March 2012}

This is what Coca Cola South Pacific is still saying about caramel colouring at livepositively.com.au:

"Colours are added to enhance the appearance of processed foods and beverages.
For example, 'Coca-Cola' contains caramel colouring, which is a widely used food and beverage colouring found in many kinds of processed food and beverages including: brown bread, buns, and chocolate. Although made from sugar, the amount present is not physiologically significant and contributes only a trace amount of kilojoules to a can of 'Coca-Cola'."
And here's Coca Cola's global press centre denying there's any problem.
While over at US National Library of Medicine National Institutes of Health this is what you find on mice fed with 4-Methylimidazole (4MI) :
"Clonic seizures, excitability, hyperactivity, and impaired gait were observed primarily in 2,500- and 5,000 ppm females. The incidence of mononuclear cell leukemia in the 5,000 ppm females was significantly greater than that in the controls. The incidences of hepatic histiocytosis, chronic inflammation, and focal fatty change were significantly increased in all exposed groups of male and female rats. The incidences of hepatocellular eosinophilic and mixed cell foci were significantly increased in 2,500 ppm males and 5,000 ppm females. Groups of 50 male and 50 female B6C3F1 mice were fed diets containing 0-, 312-, 625-, or 1,250 ppm 4MI for 106 weeks. Based on the food consumption the calculated average daily doses were approximately 40, 80, or 170 mg 4MI/kg body weight to males and females. Survival of all exposed groups of males and females was similar to that of the control groups. Mean body weights of males and females in the 1,250 ppm groups and that in the 312- and 625 ppm females were less than those of the control groups. Feed consumption by exposed groups of male and female mice was similar to that by the controls. The incidences of alveolar/bronchiolar adenoma in all exposed groups of females, alveolar/bronchiolar carcinoma in 1,250 ppm males, and alveolar/bronchiolar adenoma or carcinoma (combined) in 1,250 ppm males and 625- and 1,250 ppm females were significantly greater than those in the control groups. The incidence of alveolar epithelial hyperplasia was significantly increased in the 1,250 ppm females. 4MI is carcinogenic inducing alveolar/bronchiolar adenoma and carcinoma in male and female mice. 4MI may also induce mononuclear cell leukemia in female rats."

Pic from Google Images